That is a good question, I personally prefer my two 1960BX cabinets I have with the 2466 and that is what I use. I think the difference is voiced in the mids. I think the 425 is a better option for blues type tones but for harder rock or higher gain stuff I do prefer these 1960 vintage cabinets.
Honestly I think the biggest difference is that my 425 cabinet still isn't broke in all the way yet. I spend most of my time using my well broke in 1960s instead. My 425 cab is still "fizzy" but I know it is the breaking in issue because my original 425 I bought with this head in 2007(which I no longer have) was not fizzy at all after it was broke in all the way.
This one I have now is brand new. I bought in purple about 8 months ago only because Steve had said purple was no longer going to be available so I went out and got another 425A to have the matching cab. Going to have to spend more time with the 425 getting it broke in.
I will try to A/B them this weekend and post a clip.