Ok, here goes even with the risk of being banned from the forum because of heresy :love :
Fender Strat w/ DiMarzio HS-3 & YJM pickups (very low output)
cheap t.bone wireless
DOD YJM308 overdrive pedal, modded to exact 70's gray DOD250 specs, full gain and volume
VM2266, preamp modded to early 70's metalpanel specs, bias circuit and power amp modded to accept also EL34s, JJECC83S and E34L tubes, low dynamic range, detail on full, body about halfway, master on full
Boss Giga Delay in the loop, 450 ms delay time, ~2 repeats
two 4x12 cabinets w/ Vintage30s
amp output impedance set at 7,6 ohms, total load impedance 4 ohms
We compared a stock 2466 against my 2266, the stock 2466 preamp going into the 2266 power amp w/ E34Ls, modded 2266 preamp into the stock 2466 power amp w/ KT66s, a VM cabinet, V30 cabinets, matching and mismatching the load impedance etc etc etc.... And to our ears the above setup sounded the best